Thionyl Chloride → HCID 178503233, compound

HRID 1995360Notes

Reaction equation

HRID 1995360 reaction equation
[CH3:1][S:2][C:3]1[CH:4]=[CH:5][C:6]([C:9]([OH:11])=O)=[N:7][CH:8]=1.S(Cl)(Cl)=O.[NH2:16][C:17]1[NH:21][N:20]=[N:19][N:18]=1>>[NH:18]1[C:17]([NH:16][C:9]([C:6]2[CH:5]=[CH:4][C:3]([S:2][CH3:1])=[CH:8][N:7]=2)=[O:11])=[N:21][N:20]=[N:19]1

Participants

4

Reactant 3

HCID 24386Thionyl ChlorideHCID 127827632-Pyridinecarboxylic acid, 5-(methylthio)-HCID 178509299HCID 178509299, compound

Product 1

HCID 178503233HCID 178503233, compoundYield 34%

Procedure

0.36 g of 5-methylthio-2-pyridinecarboxylic acid, 6 ml of thionyl chloride and 0.18 g of 5-aminotetrazole are treated in the same manner as described in Example 1. The crude product thus obtained is recrystallized from a mixture of dimethylformamide and ethanol, whereby 0.17 g of N-(5-tetrazolyl)-5-methylthio-2-pyridinecarboxamide is obtained.

Workup

  1. customThe crude product thus obtained
  2. customis recrystallized from a mixture of dimethylformamide and ethanol

Sources & evidence

ORD record
ord-493cba7214c0441ab993610185627b17
Source dataset
uspto-grants-1983_09
Patent number
US04404214

Reaction notes

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