Thionyl Chloride → HCID 178522685, compound

HRID 1995361Notes

Reaction equation

HRID 1995361 reaction equation
[N+:1]([C:4]1[CH:5]=[CH:6][C:7]([C:10]([OH:12])=O)=[N:8][CH:9]=1)([O-:3])=[O:2].S(Cl)(Cl)=O.[NH2:17][C:18]1[NH:22][N:21]=[N:20][N:19]=1>>[NH:19]1[C:18]([NH:17][C:10]([C:7]2[CH:6]=[CH:5][C:4]([N+:1]([O-:3])=[O:2])=[CH:9][N:8]=2)=[O:12])=[N:22][N:21]=[N:20]1

Participants

4

Reactant 3

HCID 24386Thionyl ChlorideHCID 5204885-Nitropicolinic acidHCID 178509299HCID 178509299, compound

Product 1

HCID 178522685HCID 178522685, compoundYield 50.6%

Procedure

0.72 g of 5-nitro-2-pyridinecarboxylic acid, 13 ml of thionyl chloride and 0.37 g of 5-aminotetrazole are treated in the same manner as described in Example 1. The crude product thus obtained is recrystallized from a mixture of dimethylformamide, ethanol and water, whereby 0.51 g of N-(5-tetrazolyl)-5-nitro-2-pyridinecarboxamide is obtained.

Workup

  1. customThe crude product thus obtained
  2. customis recrystallized from a mixture of dimethylformamide, ethanol and water

Sources & evidence

ORD record
ord-fdaf5d8a8a8b42839d574cbf7bfea7a0
Source dataset
uspto-grants-1983_09
Patent number
US04404214

Reaction notes

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