3-Methylpicolinic acid → HCID 178426299, compound

HRID 1995366Notes

Reaction equation

HRID 1995366 reaction equation
[CH3:1][C:2]1[C:3]([C:8]([OH:10])=O)=[N:4][CH:5]=[CH:6][CH:7]=1.[NH2:11][C:12]1[NH:16][N:15]=[N:14][N:13]=1>>[NH:13]1[C:12]([NH:11][C:8]([C:3]2[C:2]([CH3:1])=[CH:7][CH:6]=[CH:5][N:4]=2)=[O:10])=[N:16][N:15]=[N:14]1

Participants

3

Reactant 2

HCID 2687573-Methylpicolinic acidHCID 178509299HCID 178509299, compound

Product 1

HCID 178426299HCID 178426299, compoundYield 9%

Procedure

1.49 g of 3-methyl-2-pyridinecarboxylic acid, 1.8 g of N,N'-carbonyldiimidazole and 1.2 g of 5-aminotetrazole are treated in the same manner as described in Example 2. The crude product thus obtained is recrystallized from a mixture of dimethylformamide and ethanol, whereby 0.2 g of N-(5-tetrazolyl)-3-methyl-2-pyridinecarboxamide is obtained.

Workup

  1. customThe crude product thus obtained
  2. customis recrystallized from a mixture of dimethylformamide and ethanol

Sources & evidence

ORD record
ord-7790d016bdce4032a36421c3c1d282df
Source dataset
uspto-grants-1983_09
Patent number
US04404214

Reaction notes

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