4,6-Dimethylpicolinic acid → HCID 178426477, compound

HRID 1995367Notes

Reaction equation

HRID 1995367 reaction equation
[CH3:1][C:2]1[CH:7]=[C:6]([CH3:8])[N:5]=[C:4]([C:9]([OH:11])=O)[CH:3]=1.[NH2:12][C:13]1[NH:17][N:16]=[N:15][N:14]=1>>[NH:14]1[C:13]([NH:12][C:9]([C:4]2[CH:3]=[C:2]([CH3:1])[CH:7]=[C:6]([CH3:8])[N:5]=2)=[O:11])=[N:17][N:16]=[N:15]1

Participants

3

Reactant 2

HCID 6932954,6-Dimethylpicolinic acidHCID 178509299HCID 178509299, compound

Product 1

HCID 178426477HCID 178426477, compoundYield 40.2%

Procedure

0.81 g of 4.6-dimethyl-2-pyridinecarboxylic acid, 0.86 g of N,N'-carbonyldiimidazole and 0.54 g of 5-aminotetrazole are treated in the same manner as described in Example 2. The crude product thus obtained is recrystallized from a mixture of dimethylformamide and ethanol, whereby 0.47 g of N-(5-tetrazolyl)-4,6-dimethyl-2-pyridinecarboxamide is obtained.

Workup

  1. customThe crude product thus obtained
  2. customis recrystallized from a mixture of dimethylformamide and ethanol

Sources & evidence

ORD record
ord-e0e4748b8dad4afeb47f0b38fa5eac70
Source dataset
uspto-grants-1983_09
Patent number
US04404214

Reaction notes

Loading…