5,6-Dimethylpyridine-2-carboxylic acid → HCID 178425851, compound

HRID 1995369Notes

Reaction equation

HRID 1995369 reaction equation
[CH3:1][C:2]1[CH:3]=[CH:4][C:5]([C:9]([OH:11])=O)=[N:6][C:7]=1[CH3:8].[NH2:12][C:13]1[NH:17][N:16]=[N:15][N:14]=1>>[NH:14]1[C:13]([NH:12][C:9]([C:5]2[CH:4]=[CH:3][C:2]([CH3:1])=[C:7]([CH3:8])[N:6]=2)=[O:11])=[N:17][N:16]=[N:15]1

Participants

3

Reactant 2

HCID 132095705,6-Dimethylpyridine-2-carboxylic acidHCID 178509299HCID 178509299, compound

Product 1

HCID 178425851HCID 178425851, compoundYield 55.4%

Procedure

0.55 g of 5,6-dimethyl-2-pyridinecarboxylic acid, 0.77 g of N,N'-carbonyldiimidazole and 0.48 g of 5-aminotetrazole are treated in the same manner as described in Example 2. The crude product thus obtained is recrystallized from a mixture of dimethylformamide and ethanol, whereby 0.44 g of N-(5-tetrazolyl)-5,6-dimethyl-2-pyridinecarboxamide is obtained.

Workup

  1. customThe crude product thus obtained
  2. customis recrystallized from a mixture of dimethylformamide and ethanol

Sources & evidence

ORD record
ord-84fe1d4b39c2493ba0217a002f3c820b
Source dataset
uspto-grants-1983_09
Patent number
US04404214

Reaction notes

Loading…