6-Methoxypicolinic acid → HCID 178490499, compound

HRID 1995372Notes

Reaction equation

HRID 1995372 reaction equation
[CH3:1][O:2][C:3]1[N:8]=[C:7]([C:9]([OH:11])=O)[CH:6]=[CH:5][CH:4]=1.[NH2:12][C:13]1[NH:17][N:16]=[N:15][N:14]=1>>[NH:14]1[C:13]([NH:12][C:9]([C:7]2[CH:6]=[CH:5][CH:4]=[C:3]([O:2][CH3:1])[N:8]=2)=[O:11])=[N:17][N:16]=[N:15]1

Participants

3

Reactant 2

HCID 5708916-Methoxypicolinic acidHCID 178509299HCID 178509299, compound

Product 1

HCID 178490499HCID 178490499, compoundYield 46.4%

Procedure

0.48 g of 6-methoxy-2-pyridinecarboxylic acid, 0.51 g of N,N'-carbonyldiimidazole and 0.29 g of 5-aminotetrazole are treated in the same manner as described in Example 2. The crude product thus obtained is recrystallized from a mixture of dimethylformamide, water and ethanol, whereby 0.32 g of N-(5-tetrazolyl)-6-methoxy-2-pyridinecarboxamide is obtained.

Workup

  1. customThe crude product thus obtained
  2. customis recrystallized from a mixture of dimethylformamide, water and ethanol

Sources & evidence

ORD record
ord-026878b2fd4c4a278e3344619a644804
Source dataset
uspto-grants-1983_09
Patent number
US04404214

Reaction notes

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