反应详情

253 g of 1-phenyl-3-(3'-nitrophenyl)-prop-2-en-1-one are suspended in 2.5 liters of glacial acetic acid. 196 g of concentrated sulfuric acid and 10 g of 10% strength Pd on animal charcoal are added and the mixture is hydrogenated under 1.1 bar hydrogen pressure, at 65°-70° C., until hydrogen is no longer absorbed. When the mixture has cooled, part of the acetic acid is distilled off, the residue is rendered alkaline with sodium hydroxide solution and extracted with ether, the organic phase is dried with sodium sulfate and filtered, the solvent is distilled off and the residue is then distilled. 150 g of 3-(3-phenylpropyl)-aniline, of boiling point 148° C./0.2 mbar, are obtained.

1. customis no longer absorbed
2. temperatureWhen the mixture has cooled
3. distillationpart of the acetic acid is distilled off
4. extractionextracted with ether
5. dry with materialthe organic phase is dried with sodium sulfate
6. filtrationfiltered
7. distillationthe solvent is distilled off
8. distillationthe residue is then distilled