HCID 54232542, compound → HCID 70485483, compound

HRID 1995506Notes

Reaction equation

HRID 1995506 reaction equation
[O:1]=[C:2]1[C:8]2[CH:9]=[CH:10][CH:11]=[CH:12][C:7]=2[N:6]2[CH:13]=[N:14][C:15](C(O)=O)=[C:5]2[C@@H:4]2[CH2:19][CH2:20][N:3]12>C(OCC)(=O)C>[CH:15]1[N:14]=[CH:13][N:6]2[C:7]3[CH:12]=[CH:11][CH:10]=[CH:9][C:8]=3[C:2](=[O:1])[N:3]3[CH2:20][CH2:19][C@H:4]3[C:5]=12

Participants

3

Reactant 1

HCID 54232542HCID 54232542, compound

Product 1

HCID 70485483HCID 70485483, compound

Reagents, catalysts & solvents 1

HCID 8857Ethyl AcetateSolvent

Procedure

1.3 g (4.8 mmol) of (S)-12,12a-dihydro-9-oxo-9H,11H-azeto[2,1-c]imidazo[1,5-a][1,4]benzodiazepine-1-carboxylic acid are heated to 240° until the gas evolution ceases. After recrysallization from ethyl acetate, there is obtained (S)-12,12a-dihydro-9H,11H-azeto[2,1-c]imidazo[1,5-a][1,4]benzodiazepin-9-one of melting point 195°-197°.

Sources & evidence

ORD record
ord-ff807ad178354fa0837ff1dc374eb42c
Source dataset
uspto-grants-1983_09
Patent number
US04405517

Reaction notes

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