Hydrochloric Acid → 79416-28-7

Participants

Reaction Steps

A solution of 21.1 g Boc-Phe-Met-ol in 20 ml dioxane is added at 0° C. to 130 ml 5 N HCl in dioxane. After reaction for 1 hour at 0° C., 400 ml ethyl ester are added, the precipitate filtered under suction, washed with ethyl ether and dried over P2O5 and KOH under vacuum, to yield the title compound: [α]D20 =+8.8° (c=1 in DMF), decomposition at 200° C.

Provenance & Evidence