Hydrochloric Acid → HCID 20487258, compound

HRID 1995583Notes

Reaction equation

HRID 1995583 reaction equation
[O:1]1[C:6]2[CH:7]=[CH:8][CH:9]=[CH:10][C:5]=2[O:4]C[CH:2]1[CH2:11][N:12]1[CH2:17][CH2:16][NH:15][CH2:14][CH2:13]1.Cl.[OH-].[Na+]>>[O:4]1[C:5]2[CH:10]=[CH:9][CH:8]=[CH:7][C:6]=2[O:1][CH2:2][CH:11]1[N:12]1[CH2:17][CH2:16][NH:15][CH2:14][CH2:13]1

Participants

4

Reactant 3

HCID 313Hydrochloric AcidHCID 14798Sodium HydroxideHCID 4106821-(1,4-Benzodioxan-2-ylmethyl)piperazine

Product 1

HCID 20487258HCID 20487258, compound

Procedure

33.0 g of the salt: 1-(1,4-benzodioxan-2-ylmethyl)piperazine.2 HCl was converted to the free base form by treating with aqueous NaOH. The free base was extracted into methylene chloride and the extract dried over Na2SO4. Evaporation of the solvent yielded 24.4 g of 1-(1,4-benzodioxan-2-yl)piperazine.

Workup

  1. extractionThe free base was extracted into methylene chloride
  2. dry with materialthe extract dried over Na2SO4
  3. customEvaporation of the solvent

Sources & evidence

ORD record
ord-a3219c50af2b405988b07c24aa15e317
Source dataset
uspto-grants-1983_09
Patent number
US04405622

Reaction notes

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