Peracetic Acid → HCID 53689522, compound

HRID 1995643Notes

Reaction equation

HRID 1995643 reaction equation
[CH3:1][C:2]1([CH3:16])[S:6][C:5]2=[N:7][CH:8]=[CH:9][N:4]2[C:3]1=[N:10][O:11][C:12](=[O:15])[NH:13][CH3:14].C(OO)(=[O:19])C>C(OC(=O)C)C>[CH3:1][C:2]1([CH3:16])[S:6](=[O:19])[C:5]2=[N:7][CH:8]=[CH:9][N:4]2[C:3]1=[N:10][O:11][C:12](=[O:15])[NH:13][CH3:14]

Participants

4

Reactant 2

HCID 6585Peracetic AcidHCID 54134190HCID 54134190, compound

Product 1

HCID 53689522HCID 53689522, compoundYield 70%

Reagents, catalysts & solvents 1

HCID 8857Ethyl AcetateSolvent

Procedure

A 2.0 g (8.32 mmol) quantity of 2,2-dimethyl-3-[O-(methyl carbamoyl)oximino]-2,3-dihydroimidazo[2,1-b]thiazole was dissolved in 300 ml of ethylacetate. The solution was cooled to -15° before 1.33 g (17.5 mmol) of peracetic acid was added. The reaction mixture was allowed to warm to 25° and stirred for 1 d, followed by concentration to ca. 100 ml and placing in the freezer overnight. The precipitate was collected to give 1.5 g (70%) of product. m.p. 147.5°-149°.

Workup

  1. additionwas added
  2. temperatureto warm to 25°
  3. concentrationfollowed by concentration to ca. 100 ml
  4. customplacing in the freezer overnight
  5. customThe precipitate was collected

Sources & evidence

ORD record
ord-754a3c87c361487588c5a92c25b5d0cf
Source dataset
uspto-grants-1983_09
Patent number
US04405632

Reaction notes

Loading…