1,3-diacetyl-1,3-dihydro-4-ethyl-5-(2-methoxybenzoyl)-2H-imidazole-2-one → 1,3-Diacetyl-1,3-dihydro-4-ethyl-5-[2-methoxy(thiobenzoyl)]-2H-imidazole-2-one

HRID 1995720Notes

Reaction equation

HRID 1995720 reaction equation
[C:1]([N:4]1[C:8]([C:9](=O)[C:10]2[CH:15]=[CH:14][CH:13]=[CH:12][C:11]=2[O:16][CH3:17])=[C:7]([CH2:19][CH3:20])[N:6]([C:21](=[O:23])[CH3:22])[C:5]1=[O:24])(=[O:3])[CH3:2].[S:25]([O-])([O-])(=O)=O.S(O)(O)(=O)=O.S(O)(O)(=O)=O.S(O)(O)(=O)=O.S(O)([O-])(=O)=O.[P+3]>C1(C)C=CC=CC=1>[C:1]([N:4]1[C:8]([C:9](=[S:25])[C:10]2[CH:15]=[CH:14][CH:13]=[CH:12][C:11]=2[O:16][CH3:17])=[C:7]([CH2:19][CH3:20])[N:6]([C:21](=[O:23])[CH3:22])[C:5]1=[O:24])(=[O:3])[CH3:2]

Participants

4

Reactant 2

HCID 204874941,3-diacetyl-1,3-dihydro-4-ethyl-5-(2-methoxybenzoyl)-2H-imidazole-2-oneHCID 178527676HCID 178527676, compound

Product 1

HCID 204874641,3-Diacetyl-1,3-dihydro-4-ethyl-5-[2-methoxy(thiobenzoyl)]-2H-imidazole-2-one

Reagents, catalysts & solvents 1

HCID 1140TolueneSolvent

Procedure

In 100 ml Toluene are suspended 10 g of 1,3-diacetyl-1,3-dihydro-4-ethyl-5-(2-methoxybenzoyl)-2H-imidazole-2-one and 20 g phosphorus pentasulfate. The mixture is refluxed 6 hours and the solvent evaporated to yield the title compound.

Workup

  1. temperatureThe mixture is refluxed 6 hours
  2. customthe solvent evaporated

Sources & evidence

ORD record
ord-38ca479c0a284d4e9ae1b01776b6b2ed
Source dataset
uspto-grants-1983_09
Patent number
US04405628

Reaction notes

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