Hydrochloric Acid → 6-Amino-6-desoxy-L-sorbose hydrochloride

Participants

Reaction Steps

20 g of N-tert.-butoxycarbonyl-6-amino-6-desoxy-L-sorbose were introduced in portions into a mixture of 6.4 ml of H2O and 13.2 ml of concentrated hydrochloric acid, whilst stirring and cooling. The batch was subsequently stirred for 2 hours, without cooling, and 120 ml of n-propanol were then added in the course of 2 hours. The resulting suspension of crystals was then stirred at 0° C. for 1 hour and filtered on a suction filter. The crystals were washed with a little n-propanol and dried at room temperature in a vacuum drying cabinet.

Provenance & Evidence