反应详情

20 g of N-tert.-butoxycarbonyl-6-amino-6-desoxy-L-sorbose were introduced in portions into a mixture of 6.4 ml of H2O and 13.2 ml of concentrated hydrochloric acid, whilst stirring and cooling. The batch was subsequently stirred for 2 hours, without cooling, and 120 ml of n-propanol were then added in the course of 2 hours. The resulting suspension of crystals was then stirred at 0° C. for 1 hour and filtered on a suction filter. The crystals were washed with a little n-propanol and dried at room temperature in a vacuum drying cabinet.

1. temperaturecooling
2. stirringThe batch was subsequently stirred for 2 hours
3. temperaturewithout cooling
4. additionThe resulting suspension of crystals
5. stirringwas then stirred at 0° C. for 1 hour
6. filtrationfiltered on a suction
7. filtrationfilter
8. washThe crystals were washed with a little n-propanol
9. customdried at room temperature in a vacuum
10. customdrying cabinet