Acetic Acid → Acetic Anhydride

HRID 1995733Notes

Reaction equation

HRID 1995733 reaction equation
[C:1]([CH2:4][CH2:5][C:6]1[C:7](=[O:17])[N:8]([NH:13]C(C)=O)[C:9]([SH:12])=[N:10][N:11]=1)([OH:3])=[O:2].[C:18](O)(=[O:20])[CH3:19]>>[C:18]([O:3][C:1](=[O:2])[CH3:4])(=[O:20])[CH3:19].[C:1]([CH2:4][CH2:5][C:6]1[C:7](=[O:17])[N:8]([NH2:13])[C:9]([SH:12])=[N:10][N:11]=1)([OH:3])=[O:2]

Participants

4

Reactant 2

HCID 176Acetic AcidHCID 178475128HCID 178475128, compound

Product 2

HCID 7918Acetic AnhydrideHCID 178514283HCID 178514283, compound

Procedure

Mixed anhydride of acetic acid and 6-(2-carboxyethyl)-3-mercapto-4-acetamino-1,2,4-triazin-5-one. The vacuum dried (55° C., 0.05 mm, 4 hours) product obtained from the reaction of acetic anhydride and 6-(2-carboxyethyl)-3-mercapto-4-amino-1,2,4-triazin-5-one at 145° C. (bath temperature) for 8 hours as described in Example 1 (but not reacted with t-butanol) is separated. Mp. 95°-100° C.; dec. 130° C. Insoluble in water, alcohol, and t-butyl alcohol; soluble in acetone, chloroform, and acetonitrile. Anal. Calcd. for C14H20O5N4S: N, 20.59; S, 11.76. Found: N, 20.56; S, 11.68.

Workup

  1. customThe vacuum dried (55° C., 0.05 mm, 4 hours) product

Sources & evidence

ORD record
ord-9fdc5e5e4df74e0f9a910e0ec7cdd2db
Source dataset
uspto-grants-1983_09
Patent number
US04405779

Reaction notes

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