Acetic Acid → Acetic Anhydride

Participants

Reaction Steps

Mixed anhydride of acetic acid and 6-(2-carboxyethyl)-3-mercapto-4-acetamino-1,2,4-triazin-5-one. The vacuum dried (55° C., 0.05 mm, 4 hours) product obtained from the reaction of acetic anhydride and 6-(2-carboxyethyl)-3-mercapto-4-amino-1,2,4-triazin-5-one at 145° C. (bath temperature) for 8 hours as described in Example 1 (but not reacted with t-butanol) is separated. Mp. 95°-100° C.; dec. 130° C. Insoluble in water, alcohol, and t-butyl alcohol; soluble in acetone, chloroform, and acetonitrile. Anal. Calcd. for C14H20O5N4S: N, 20.59; S, 11.76. Found: N, 20.56; S, 11.68.

Provenance & Evidence