Phosphorus oxychloride → 6-Chloropurine

HRID 1995741Notes

Reaction equation

HRID 1995741 reaction equation
[NH:1]1[C:9](=O)[C:8]2[NH:7][CH:6]=[N:5][C:4]=2[N:3]=[CH:2]1.P(Cl)(Cl)([Cl:13])=O>>[Cl:13][C:9]1[N:1]=[CH:2][N:3]=[C:4]2[C:8]=1[NH:7][CH:6]=[N:5]2

Participants

3

Reactant 2

HCID 24813Phosphorus oxychlorideHCID 135398638Hypoxanthine

Product 1

HCID 53592776-Chloropurine

Procedure

reacting hypoxanthine and phosphorus oxychloride in the presence of an organic base to form 6-chloropurine;

Sources & evidence

ORD record
ord-3cf50873f22042a5b2eaa9706167dccf
Source dataset
uspto-grants-1983_09
Patent number
US04405781

Reaction notes

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