HuagongsheHuagongshe Chemistry Print Report · For research reference only
Sodium Hydroxide → HCID 3062229, compound
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | Sodium Hydroxide | HCID 14798 | — |
| Reactant | Tetrafluoro-m-phenylenediamine dihydrochloride | HCID 149026 | — |
| Reactant | HCID 12674078 | HCID 12674078 | — |
| Catalyst | Benzyl triethylammonium chloride | HCID 66133 | — |
| Solvent | Water | HCID 962 | — |
| Solvent | Chloroform | HCID 6212 | — |
| Product | HCID 3062229 | HCID 3062229 | — |
Reaction Steps
The operation is as in Example 1, but starting from 11 g of 4-[2-(5-chloro-3-indolyl)-ethyl]-piperidine and 0.21 g of benzyltriethylammonium chloride in suspension in 100 ml of chloroform and 12.5 g of sodium hydroxide in solution in 25 ml of water. 2 g of 3,6-dichloro-4-[2-(4-piperidyl)-ethyl]-quinoline are finally obtained in the form of the dihydrochloride melting at 248° C.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US04405789 |
| Source dataset | uspto-grants-1983_09 |
| ORD ID | ord-37577a75db154fe48bd5229c1616fde0 |
| Source note | uspto-grants-1983_09 |