HuagongsheHuagongshe Chemistry Print Report · For research reference only
Hydrochloric Acid → HCID 3062241, compound
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | Hydrochloric Acid | HCID 313 | — |
| Reactant | Chloroform | HCID 6212 | — |
| Reactant | Sodium Hydroxide | HCID 14798 | — |
| Reactant | HCID 12805990 | HCID 12805990 | — |
| Catalyst | Benzyl triethylammonium chloride | HCID 66133 | — |
| Solvent | Water | HCID 962 | — |
| Product | HCID 3062241 | HCID 3062241 | — |
Reaction Steps
The operation is as in Example 1, but starting from 8.3 g of 4-[2-(2-indolyl)-ethyl]-piperidine and 0.18 g of triethylbenzylammonium chloride in 90 ml of chloroform, and 11 g of sodium hydroxide in solution in 22 ml of water. 1.45 g of 3-chloro-2-[2-(4-piperidyl)-ethyl]-quinoline are obtained the monohydrochloride of which melts at 162° C.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US04405789 |
| Source dataset | uspto-grants-1983_09 |
| ORD ID | ord-9745302f843e4e68b74547c399d8f678 |
| Source note | uspto-grants-1983_09 |