Phenol → 2-Isopropylphenol

HRID 1995780Notes

Reaction equation

HRID 1995780 reaction equation
[C:1]1([OH:7])[CH:6]=[CH:5][CH:4]=[CH:3][CH:2]=1.[CH:8](O)([CH3:10])[CH3:9].C=CC>C(C1C=C(O)C=CC=1)(C)C>[CH:8]([C:2]1[CH:3]=[CH:4][CH:5]=[CH:6][C:1]=1[OH:7])([CH3:10])[CH3:9]

Participants

5

Reactant 3

HCID 996PhenolHCID 3776IsopropanolHCID 8252Propylene

Product 1

HCID 69432-Isopropylphenol

Reagents, catalysts & solvents 1

HCID 120593-IsopropylphenolSolvent

Procedure

Organic compound mixtures enriched in meta-isopropylphenol are prepared by alkylating phenol with isopropanol or propylene to form mixtures of isopropylphenol isomers and by subsequently selectively cracking the para-isopropylphenol isomer from such a mixture over a ZSM-5 type cracking catalyst. Concentration of the para-isomer is thereby selectively reduced relative to the meta-isomer and the meta-isopropylphenol isomer can be further separated from the remaining mixture by fractionation procedures.

Workup

  1. customare prepared

Sources & evidence

ORD record
ord-c84ab586a2a54dc08959de544c98982d
Source dataset
uspto-grants-1983_09
Patent number
US04405818

Reaction notes

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