O-Cresol → 2,6-Dimethylphenol

HRID 1995859Notes

Reaction equation

HRID 1995859 reaction equation
[C:1]1([CH3:8])[C:6]([OH:7])=[CH:5][CH:4]=[CH:3][CH:2]=1.[CH3:9]O>[O-2].[Fe+2].[O-2].[Zr+4].[O-2].[O-2].[Cr+3].[O-2].[O-2].[Cr+3].O>[C:6]1([OH:7])[C:5]([CH3:9])=[CH:4][CH:3]=[CH:2][C:1]=1[CH3:8]

Participants

7

Reactant 2

HCID 335O-CresolHCID 887Methanol

Product 1

HCID 113352,6-Dimethylphenol

Reagents, catalysts & solvents 4

HCID 165971Chromium oxideCatalystHCID 449809Ferrous oxideCatalystHCID 6452892Zirconium oxideCatalystHCID 962WaterSolvent

Procedure

o-cresol, methanol and water in a molar ratio of 1:2,5:2,5 were reacted in the same way as in Example 1. The catalyst consisted of iron oxide, zirconium oxide, chromium oxide and lanthanium oxide in a molar ratio of 100:3:2:0,5. After working up, 2,6-xylenol was obtained with a selectivity of 98,2%.

Sources & evidence

ORD record
ord-d7f4ec7a845f49398c98356083a6c42b
Source dataset
uspto-grants-1983_09
Patent number
US04406824

Reaction notes

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