HuagongsheHuagongshe Chemistry Print Report · For research reference only
Sodium Hydroxide → 2,6-Difluorobenzonitrile
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | Sodium Hydroxide | HCID 14798 | — |
| Reactant | 3-Chloro-2,6-difluorobenzonitrile | HCID 13175231 | — |
| Catalyst | HCID 178418390 | HCID 178418390 | — |
| Solvent | Water | HCID 962 | — |
| Product | 2,6-Difluorobenzonitrile | HCID 74695 | 70.2% |
Reaction Steps
In the same manner as in the process of the reduction step of Example 1, the reaction was carried out at 40° C. for 2.5 hours by using 10 g of 3-chloro-2,6-difluorobenzonitrile, 60 g of water, 0.25 g of palladium-carbon catalyst and 3 g of sodium hydroxide, and refinement was carried out to obtain 5.63 g of 2,6-difluorobenzonitrile.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US04406841 |
| Source dataset | uspto-grants-1983_09 |
| ORD ID | ord-34571d0dd3b448d0b9dc8cef745087d1 |
| Source note | uspto-grants-1983_09 |