Acetic Anhydride → HCID 178475134, compound

HRID 1995901Notes

Reaction equation

HRID 1995901 reaction equation
C(O[C:5](=[O:7])[CH3:6])(=O)C.[Cl:8][C:9]1[CH:14]=[CH:13][C:12]([C:15]2[N:20]=[C:19]([OH:21])[N:18]=[C:17]([NH:22][NH2:23])[N:16]=2)=[CH:11][CH:10]=1>C1COCC1>[C:5]([NH:23][NH:22][C:17]1[N:16]=[C:15]([C:12]2[CH:11]=[CH:10][C:9]([Cl:8])=[CH:14][CH:13]=2)[N:20]=[C:19]([OH:21])[N:18]=1)(=[O:7])[CH3:6]

Participants

4

Reactant 2

HCID 7918Acetic AnhydrideHCID 178514359HCID 178514359, compound

Product 1

HCID 178475134HCID 178475134, compound

Reagents, catalysts & solvents 1

HCID 8028TetrahydrofuranSolvent

Procedure

Acetic anhydride (6 ml) is added to a suspension of 6-(4-chlorophenyl)-4-hydrazino-2-hydroxy-1,3,5-triazine in THF (500 ml) and the mixture stirred under reflux for 21/2 hours. The mixture is cooled to RT overnight and the solid filtered, washed with ether and air dried, yielding 13.95 g of the solid. The solid is washed in 500 ml of boiling dioxane, filtered, washed with ether and air dried, leaving 13.8 g of the acetyl hydrazine triazine, m.p. 250° C.

Workup

  1. temperatureunder reflux for 21/2 hours
  2. filtrationthe solid filtered
  3. washwashed with ether and air
  4. customdried

Sources & evidence

ORD record
ord-af521f0d63d543ef97a963bab76462de
Source dataset
uspto-grants-1983_09
Patent number
US04406897

Reaction notes

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