HuagongsheHuagongshe Chemistry Print Report · For research reference only
tert-Butyl 3-amino-3-methylpyrrolidine-1-carboxylate → Tert-butyl 3-(4-chloro-2-morpholin-4-yl-5,6-dihydropyrrolo[2,3-d]pyrimidin-7-yl)-3-methylpyrrolidine-1-carboxylate
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | tert-Butyl 3-amino-3-methylpyrrolidine-1-carboxylate | HCID 57415917 | — |
| Reactant | HCID 178505284 | HCID 178505284 | — |
| Reagent | Cesium fluoride | HCID 25953 | — |
| Solvent | 2-Methyl-2-butanol | HCID 6405 | — |
| Product | Tert-butyl 3-(4-chloro-2-morpholin-4-yl-5,6-dihydropyrrolo[2,3-d]pyrimidin-7-yl)-3-methylpyrrolidine-1-carboxylate | HCID 123726091 | — |
| Internal standard | 9-Phenylanthracene | HCID 11766 | — |
Reaction Conditions
| Temperature | 120 °C |
|---|
Provenance & Evidence
| DOI | 10.1038/s41557 |
|---|---|
| Source dataset | 39k HTE dataset from Pfizer |
| ORD ID | ord-e1908317e7a94359b59c024e30e78245 |
| Source note | 39k HTE dataset from Pfizer |