Dichloromethane → 3-cyano-N-[2-(4-cyanophenyl)-4-hydroxybutyl]-N-methyl-1-naphthamide

HRID 199770Notes

Reaction equation

HRID 199770 reaction equation
[C:25](#[N:26])[c:27]1[cH:28][c:29]([C:37](=[O:38])[Cl:39])[c:30]2[cH:31][cH:32][cH:33][cH:34][c:35]2[cH:36]1.[CH:16]([N:17]([CH2:18][CH3:19])[CH:20]([CH3:21])[CH3:22])([CH3:23])[CH3:24].[Cl:40][CH2:41][Cl:42].[OH:1][CH2:2][CH2:3][CH:4]([CH2:5][NH:6][CH3:7])[c:8]1[cH:9][cH:10][c:11]([C:12]#[N:13])[cH:14][cH:15]1>>[OH:1][CH2:2][CH2:3][CH:4]([CH2:5][N:6]([CH3:7])[C:37]([c:29]1[cH:28][c:27]([C:25]#[N:26])[cH:36][c:35]2[c:30]1[cH:31][cH:32][cH:33][cH:34]2)=[O:38])[c:8]1[cH:9][cH:10][c:11]([C:12]#[N:13])[cH:14][cH:15]1

Participants

5

Reactant 4

HCID 6344DichloromethaneHCID 81531DiisopropylethylamineHCID 226366863-Cyano-1-naphthoyl chlorideHCID 689779184-{3-Hydroxy-1-[(methylamino)methyl]propyl}benzonitrile

Product 1

HCID 689764513-cyano-N-[2-(4-cyanophenyl)-4-hydroxybutyl]-N-methyl-1-naphthamide

Sources & evidence

ORD record
ord-a4ded852fd7749dc8da40e0e603e0f17
Source dataset
Training data from https://doi.org/10.1039/C8SC04228D (6/10)

Reaction notes

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