Hydrochloric Acid → [2,5-Bis(trifluoromethyl)phenyl]{4-[4-(2-phenylethyl)-1,3-thiazol-2-yl]piperidin-1-yl}methanone
Reaction equation
[ClH:1].[F:48][C:49]([c:50]1[c:51]([C:60](=[O:61])[Cl:62])[cH:52][c:53]([C:56]([F:57])([F:58])[F:59])[cH:54][cH:55]1)([F:63])[F:64].[c:21]1([CH2:22][CH2:23][c:24]2[n:25][c:26]([CH:27]3[CH2:28][CH2:29][N:30]([C:31](=[O:32])[CH2:33][c:34]4[cH:35][cH:36][s:37][cH:38]4)[CH2:39][CH2:40]3)[s:41][cH:42]2)[cH:43][cH:44][cH:45][cH:46][cH:47]1.[c:2]1([CH2:8][CH2:9][c:10]2[n:11][c:12]([CH:15]3[CH2:16][CH2:17][NH:18][CH2:19][CH2:20]3)[s:13][cH:14]2)[cH:3][cH:4][cH:5][cH:6][cH:7]1>>[c:2]1([CH2:8][CH2:9][c:10]2[n:11][c:12]([CH:15]3[CH2:16][CH2:17][N:18]([C:60]([c:51]4[c:50]([C:49]([F:48])([F:63])[F:64])[cH:55][cH:54][c:53]([C:56]([F:57])([F:58])[F:59])[cH:52]4)=[O:61])[CH2:19][CH2:20]3)[s:13][cH:14]2)[cH:3][cH:4][cH:5][cH:6][cH:7]1Participants
5
Reactant 4
Product 1
Sources & evidence
- ORD record
- ord-8841de077b03458fb295f14aeccdef18
- Source dataset
- Training data from https://doi.org/10.1039/C8SC04228D (6/10)
Reaction notes
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