Pyridine → tert-Butyl 4-(((6-cyano-4-(3-fluoro-4-((phenoxycarbonyl)amino)phenoxy)-7-quinolyl)oxy)methyl)-1-piperidinecarboxylate
Reaction equation
[Cl:43][C:44](=[O:45])[O:46][c:47]1[cH:48][cH:49][cH:50][cH:51][cH:52]1.[NH2:1][c:2]1[c:3]([F:36])[cH:4][c:5]([O:6][c:7]2[cH:8][cH:9][n:10][c:11]3[cH:12][c:13]([O:19][CH2:20][CH:21]4[CH2:22][CH2:23][N:24]([C:27](=[O:28])[O:29][C:30]([CH3:31])([CH3:32])[CH3:33])[CH2:25][CH2:26]4)[c:14]([C:17]#[N:18])[cH:15][c:16]23)[cH:34][cH:35]1.[O:53]1[CH2:54][CH2:55][CH2:56][CH2:57]1.[cH:37]1[cH:38][cH:39][n:40][cH:41][cH:42]1>>[NH:1]([c:2]1[c:3]([F:36])[cH:4][c:5]([O:6][c:7]2[cH:8][cH:9][n:10][c:11]3[cH:12][c:13]([O:19][CH2:20][CH:21]4[CH2:22][CH2:23][N:24]([C:27](=[O:28])[O:29][C:30]([CH3:31])([CH3:32])[CH3:33])[CH2:25][CH2:26]4)[c:14]([C:17]#[N:18])[cH:15][c:16]23)[cH:34][cH:35]1)[C:44](=[O:45])[O:46][c:47]1[cH:48][cH:49][cH:50][cH:51][cH:52]1Participants
5
Reactant 4
Product 1
Sources & evidence
- ORD record
- ord-bd195f4ab2734e1b8f586fc881d76b19
- Source dataset
- Training data from https://doi.org/10.1039/C8SC04228D (6/10)
Reaction notes
Loading…