1,1'-Biphenyl-4-yl-boronic acid → Ethyl 2-fluoro-2-(4-phenylphenyl)acetate
Reaction equation
OB([c:1]1[cH:6][cH:5][c:4]([c:7]2[cH:12][cH:11][cH:10][cH:9][cH:8]2)[cH:3][cH:2]1)O.[CH3:13][CH2:14][O:15][C:16]([CH:18](Br)[F:19])=[O:17]>>[CH3:13][CH2:14][O:15][C:16]([CH:18]([c:1]1[cH:6][cH:5][c:4]([c:7]2[cH:12][cH:11][cH:10][cH:9][cH:8]2)[cH:3][cH:2]1)[F:19])=[O:17]Participants
8
Reactant 2
Product 1
Reagents, catalysts & solvents 5
Conditions
- Temperature
- 100 °C
Sources & evidence
- ORD record
- ord-4db121a7a85f43b7877ae1591f0b9532
- Source dataset
- 39k HTE dataset from Pfizer
- Original link
- View source
Reaction notes
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