Hydrochloric Acid → 5-(Chloromethyl)-2,3-dimethoxypyridine

HRID 200395Notes

Reaction equation

HRID 200395 reaction equation
[C:35](#[N:36])[CH3:37].[Cl:3][c:4]1[c:5]([N:11]=[C:12]2[N:13]([O:17][CH2:18][c:19]3[cH:20][c:21]([O:27][CH3:28])[c:22]([O:25][CH3:26])[n:23][cH:24]3)[CH2:14][CH2:15][NH:16]2)[c:6]([Cl:10])[cH:7][cH:8][cH:9]1.[ClH:1].[ClH:2].[O:29]1[CH2:30][CH2:31][O:32][CH2:33][CH2:34]1>>[Cl:1][CH2:18][c:19]1[cH:20][c:21]([O:27][CH3:28])[c:22]([O:25][CH3:26])[n:23][cH:24]1.[Cl:3][c:4]1[c:5]([N:11]=[C:12]2[N:13]([OH:17])[CH2:14][CH2:15][NH:16]2)[c:6]([Cl:10])[cH:7][cH:8][cH:9]1

Participants

6

Reactant 4

HCID 313Hydrochloric Acid2×HCID 6342AcetonitrileHCID 312751,4-DioxaneHCID 178492647HCID 178492647, compound

Product 2

HCID 204014705-(Chloromethyl)-2,3-dimethoxypyridineHCID 178526276HCID 178526276, compound

Sources & evidence

ORD record
ord-d4df2c385a274e6187e73bc1aa3e5238
Source dataset
Training data from https://doi.org/10.1039/C8SC04228D (6/10)

Reaction notes

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