Dichloromethane → [4-(3,4,5,6-tetrahydro-2H-[1,2']bipyrazinyl-3'-yl)-phenyl]-methanol

HRID 200427Notes

Reaction equation

HRID 200427 reaction equation
[C:1]([O:2][C:3](=[O:4])[N:8]1[CH2:9][CH2:10][N:11]([c:14]2[n:15][cH:16][cH:17][n:18][c:19]2-[c:20]2[cH:21][cH:22][c:23]([CH2:26][OH:27])[cH:24][cH:25]2)[CH2:12][CH2:13]1)([CH3:5])([CH3:6])[CH3:7].[Cl:35][CH2:36][Cl:37].[OH:28][C:29]([C:30]([F:31])([F:32])[F:33])=[O:34]>>[NH:8]1[CH2:9][CH2:10][N:11]([c:14]2[n:15][cH:16][cH:17][n:18][c:19]2-[c:20]2[cH:21][cH:22][c:23]([CH2:26][OH:27])[cH:24][cH:25]2)[CH2:12][CH2:13]1

Participants

4

Reactant 3

HCID 6344DichloromethaneHCID 6422Trifluoroacetic acidHCID 685946841,1-Dimethylethyl 4-[3-[4-(hydroxymethyl)phenyl]-2-pyrazinyl]-1-piperazinecarboxylate

Product 1

HCID 68594908[4-(3,4,5,6-tetrahydro-2H-[1,2']bipyrazinyl-3'-yl)-phenyl]-methanol

Sources & evidence

ORD record
ord-c2a48118036b4c68865660cce4556f86
Source dataset
Training data from https://doi.org/10.1039/C8SC04228D (6/10)

Reaction notes

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