1-(5-Fluoro-2-methoxyphenyl)ethan-1-one → (1R)-1-(5-fluoro-2-methoxyphenyl)ethan-1-ol
Reaction equation
[CH3:1][O:2][c:3]1[c:9]([C:10]([CH3:12])=[O:11])[cH:8][c:6]([F:7])[cH:5][cH:4]1>>[CH3:1][O:2][c:3]1[c:9]([C@H:10]([OH:11])[CH3:12])[cH:8][c:6]([F:7])[cH:5][cH:4]1Participants
4
Reactant 1
Product 1
Reagents, catalysts & solvents 2
Conditions
- Temperature
- 50 °C
Sources & evidence
- ORD record
- ord-f7a29c12bc6945298e010a5cadcc7060
- Source dataset
- 39k HTE dataset from Pfizer
- Original link
- View source
Reaction notes
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