1-[2-(2,2,2-Trifluoroethoxy)phenyl]piperazine → Hydrochloric Acid

HRID 200679Notes

Reaction equation

HRID 200679 reaction equation
[Cl:19][CH2:20][CH2:21][CH2:22][n:23]1[c:24](=[O:38])[n:25](-[c:31]2[cH:32][cH:33][c:34]([F:37])[cH:35][cH:36]2)[cH:26][c:27]([CH3:30])[c:28]1=[O:29].[F:1][C:2]([CH2:3][O:4][c:5]1[c:6]([N:11]2[CH2:12][CH2:13][NH:14][CH2:15][CH2:16]2)[cH:7][cH:8][cH:9][cH:10]1)([F:17])[F:18]>>[ClH:19].[F:1][C:2]([CH2:3][O:4][c:5]1[c:6]([N:11]2[CH2:12][CH2:13][N:14]([CH2:20][CH2:21][CH2:22][n:23]3[c:24](=[O:38])[n:25](-[c:31]4[cH:32][cH:33][c:34]([F:37])[cH:35][cH:36]4)[cH:26][c:27]([CH3:30])[c:28]3=[O:29])[CH2:15][CH2:16]2)[cH:7][cH:8][cH:9][cH:10]1)([F:17])[F:18]

Participants

4

Reactant 2

HCID 104915651-[2-(2,2,2-Trifluoroethoxy)phenyl]piperazineHCID 545424933-(3-chloropropyl)-1-(4-fluorophenyl)-5-methyl-2,4(1H,3H)-pyrimidinedione

Product 2

HCID 313Hydrochloric AcidHCID 701982051-(4-Fluorophenyl)-5-methyl-3-[3-[4-[2-(2,2,2-trifluoroethoxy)phenyl]piperazin-1-yl]propyl]pyrimidine-2,4-dione

Sources & evidence

ORD record
ord-3315ee4bc11648beacf5e2f7355da69f
Source dataset
Training data from https://doi.org/10.1039/C8SC04228D (6/10)

Reaction notes

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