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HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 20073Generated: October 25, 2026

Trifluoroacetic acid → Trifluoroacetic acid

https://huagongshe.com/reaction/20073

Reaction equation

Participants

RoleNameHCIDCharge
ReactantTrifluoroacetic acidHCID 6422—
ReactantHCID 178452066HCID 178452066—
SolventDichloromethaneHCID 6344—
ProductTrifluoroacetic acidHCID 6422—
ProductHCID 178518622HCID 178518622—

Reaction Steps

tert-Butyl 4-(4-oxido-2-oxo-2,3-dihydro-1H-imidazo[4,5-b]pyridin-1-yl)piperidine-1-carboxylate (45 mg, 0.135 mmol) was dissolved in dichloromethane (10 mL) and trifluoroacetic acid (5 mL) was added at room temperature. After 3 h, the volatiles were removed in vacuo to give the title compound as its TFA salt. MS 235.2 (M+1).

Provenance & Evidence

DOI10.6084/m9.figshare.5104873.v1
Patent numberUS07745427B2
Source datasetuspto-grants-2010_06
ORD IDord-7b64a62b94384540899888cc3bda1e72
Source noteuspto-grants-2010_06