6-Bromoquinoline → HCID 178454372, compound

HRID 2012834Notes

Reaction equation

HRID 2012834 reaction equation
Br[c:1]1[cH:10][c:9]([c:4]2[cH:3][cH:2]1)[cH:8][cH:7][cH:6][n:5]2.[CH3:11][C:12]([O:15][C:16]([NH:18][NH:19][C:20]([O:22][C:23]([CH3:26])([CH3:25])[CH3:24])=[O:21])=[O:17])([CH3:14])[CH3:13]>>[CH3:11][C:12]([O:15][C:16]([NH:18][N:19]([c:1]1[cH:10][c:9]([c:4]2[cH:3][cH:2]1)[cH:8][cH:7][cH:6][n:5]2)[C:20]([O:22][C:23]([CH3:26])([CH3:25])[CH3:24])=[O:21])=[O:17])([CH3:14])[CH3:13]

Participants

7

Reactant 2

HCID 792436-BromoquinolineHCID 85431Di-tert-butyl bicarbamate

Product 1

HCID 178454372HCID 178454372, compound

Reagents, catalysts & solvents 4

HCID 33931062,N'3,N'3,N3,N3,N'5,N'5,N5,N5-nonamethyl-2,4,6-triaza-3lambda5,5lambda5-diphosphaocta-3,5-diene-3,3,5,5-tetramineReagentHCID 178420029HCID 178420029, compoundCatalystHCID 64052-Methyl-2-butanolSolventHCID 117669-PhenylanthraceneInternal standard

Conditions

Temperature
90 °C

Sources & evidence

ORD record
ord-71d2e8ee1f704a0ea33938f75db1f4ea
Source dataset
39k HTE dataset from Pfizer
Original link
View source

Reaction notes

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