Hydrochloric Acid → {3-[4-(5-Cyclopropylisoxazol-4-yl)benzyl]-4-difluoromethoxy-2-ethyl-8-fluoroquinolin-5-yloxy}acetic acid methyl ester
Reaction equation
[Br:34][c:35]1[cH:36][n:37][o:38][c:39]1[CH:40]1[CH2:41][CH2:42]1.[C:43](=[O:44])([O-:45])[OH:46].[CH3:50][O:51][CH2:52][CH2:53][O:54][CH3:55].[ClH:48].[F:1][CH:2]([O:3][c:4]1[c:5]([CH2:23][c:24]2[cH:25][cH:26][c:27]([B:30]([OH:31])[OH:32])[cH:28][cH:29]2)[c:6]([CH2:21][CH3:22])[n:7][c:8]2[c:9]([F:20])[cH:10][cH:11][c:12]([O:14][CH2:15][C:16](=[O:17])[O:18][CH3:19])[c:13]12)[F:33].[Na+:47].[OH2:49]>>[F:1][CH:2]([O:3][c:4]1[c:5]([CH2:23][c:24]2[cH:25][cH:26][c:27](-[c:35]3[cH:36][n:37][o:38][c:39]3[CH:40]3[CH2:41][CH2:42]3)[cH:28][cH:29]2)[c:6]([CH2:21][CH3:22])[n:7][c:8]2[c:9]([F:20])[cH:10][cH:11][c:12]([O:14][CH2:15][C:16](=[O:17])[O:18][CH3:19])[c:13]12)[F:33]Participants
8
Reactant 7
Product 1
Sources & evidence
- ORD record
- ord-e3910110e47f4cda966cef65310f4d04
- Source dataset
- Training data from https://doi.org/10.1039/C8SC04228D (6/10)
Reaction notes
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