2-Aminopyrimidine-5-boronic acid, pinacol ester → HCID 178508374, compound
Reaction equation
CC1(C(C)(C)OB([c:1]2[cH:7][n:6][c:4]([NH2:5])[n:3][cH:2]2)O1)C.[Cl:8][CH2:9][CH2:10][c:11]1[c:17](Cl)[n:16][c:15]([N:18]2[CH2:23][CH2:22][O:21][CH2:20][CH2:19]2)[n:14][c:12]1[Cl:13]>>[NH2:5][c:4]1[n:6][cH:7][c:1]([c:17]2[c:11]([CH2:10][CH2:9][Cl:8])[c:12]([Cl:13])[n:14][c:15]([N:18]3[CH2:23][CH2:22][O:21][CH2:20][CH2:19]3)[n:16]2)[cH:2][n:3]1Participants
8
Reactant 2
Product 1
Reagents, catalysts & solvents 5
Conditions
- Temperature
- 60 °C
Sources & evidence
- ORD record
- ord-ce7100fd30094cce9ec4a95be193dbc9
- Source dataset
- 39k HTE dataset from Pfizer
- Original link
- View source
Reaction notes
Loading…