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HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 201528Generated: October 29, 2026

Tetrahydrofuran → 1-(4-Trifluoromethyl-6-chloropyrimidin-5-yl)-1-(2-chloro-4-methoxypyrimidin-5-yl)methanol

https://huagongshe.com/reaction/201528

Reaction equation

Participants

RoleNameHCIDCharge
ReactantTetrahydrofuranHCID 8028—
ReactantLithium ionHCID 28486—
ReactantDiisopropylamideHCID 5062348—
Reactant4-Chloro-6-(trifluoromethyl)pyrimidineHCID 11542881—
Reactant2-Chloro-4-methoxypyrimidine-5-carbaldehydeHCID 15147553—
Product1-(4-Trifluoromethyl-6-chloropyrimidin-5-yl)-1-(2-chloro-4-methoxypyrimidin-5-yl)methanolHCID 19702797—

Provenance & Evidence

DOI10.1039/C8SC04228D
Source datasetTraining data from https://doi.org/10.1039/C8SC04228D (6/10)
ORD IDord-6a4f0a3db12f42438fbd5f24ff802c69
Source noteTraining data from https://doi.org/10.1039/C8SC04228D (6/10)