Tetrahydrofuran → 1-(4-Trifluoromethyl-6-chloropyrimidin-5-yl)-1-(2-chloro-4-methoxypyrimidin-5-yl)methanol
Reaction equation
[CH2:31]1[O:32][CH2:33][CH2:34][CH2:35]1.[CH:12]([N-:13][CH:14]([CH3:15])[CH3:16])([CH3:17])[CH3:18].[Cl:1][c:2]1[n:3][cH:4][n:5][c:6]([C:8]([F:9])([F:10])[F:11])[cH:7]1.[Cl:20][c:21]1[n:22][cH:23][c:24]([CH:29]=[O:30])[c:25]([O:27][CH3:28])[n:26]1.[Li+:19]>>[Cl:1][c:2]1[n:3][cH:4][n:5][c:6]([C:8]([F:9])([F:10])[F:11])[c:7]1[CH:29]([c:24]1[cH:23][n:22][c:21]([Cl:20])[n:26][c:25]1[O:27][CH3:28])[OH:30]Participants
6
Reactant 5
Product 1
Sources & evidence
- ORD record
- ord-6a4f0a3db12f42438fbd5f24ff802c69
- Source dataset
- Training data from https://doi.org/10.1039/C8SC04228D (6/10)
Reaction notes
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