HCID 178483110, compound → HCID 178486944, compound

HRID 2016452Notes

Reaction equation

HRID 2016452 reaction equation
[CH3:1][O:2][c:3]1[c:9]([NH2:10])[n:8][c:7](Br)[c:5]([Br:6])[cH:4]1.[CH3:11][N:12]([C:22]([O:24][C:25]([CH3:28])([CH3:27])[CH3:26])=[O:23])[CH2:13][c:14]1[c:21]([Sn](C)(C)C)[c:18]([C:19]#[N:20])[n:16]([CH3:17])[n:15]1>>[CH3:1][O:2][c:3]1[c:9]([NH2:10])[n:8][c:7]([c:21]2[c:18]([C:19]#[N:20])[n:16]([CH3:17])[n:15][c:14]2[CH2:13][N:12]([C:22]([O:24][C:25]([CH3:28])([CH3:27])[CH3:26])=[O:23])[CH3:11])[c:5]([Br:6])[cH:4]1

Participants

6

Reactant 2

HCID 178483110HCID 178483110, compoundHCID 178486943HCID 178486943, compound

Product 1

HCID 178486944HCID 178486944, compound

Reagents, catalysts & solvents 3

HCID 10876480Bis(tri-o-tolylphosphine)palladium(II) DichlorideCatalystHCID 679Dimethyl SulfoxideSolventHCID 117669-PhenylanthraceneInternal standard

Conditions

Temperature
25 °C

Sources & evidence

ORD record
ord-90135597b2a6410c9f759f48885c8d1b
Source dataset
39k HTE dataset from Pfizer
Original link
View source

Reaction notes

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