HCID 56655901, compound → HCID 178456409, compound

HRID 2017611Notes

Reaction equation

HRID 2017611 reaction equation
F[B-]([C:1]([CH2:3][N:4]1[CH2:9][CH2:8][O:7][CH2:6][CH2:5]1)=[CH2:2])(F)F.[CH3:10][c:11]1[n:39][c:30]([O:31][CH2:32][c:33]2[cH:38][cH:37][cH:36][cH:35][cH:34]2)[c:15]([CH2:16][N:17]3[C:28](=[O:29])[c:27]([c:20]4[CH2:19][CH2:18]3)[c:25]([Cl:26])[c:24](Br)[cH:23][c:21]4[Cl:22])[c:13]([CH3:14])[cH:12]1>>[CH3:10][c:11]1[n:39][c:30]([O:31][CH2:32][c:33]2[cH:38][cH:37][cH:36][cH:35][cH:34]2)[c:15]([CH2:16][N:17]3[C:28](=[O:29])[c:27]([c:20]4[CH2:19][CH2:18]3)[c:25]([Cl:26])[c:24]([C:1]([CH2:3][N:4]5[CH2:9][CH2:8][O:7][CH2:6][CH2:5]5)=[CH2:2])[cH:23][c:21]4[Cl:22])[c:13]([CH3:14])[cH:12]1

Participants

8

Reactant 2

HCID 56655901HCID 56655901, compoundHCID 867237282-((2-(benzyloxy)-4,6-dimethylpyridin-3-yl)methyl)-7-bromo-5,8-dichloro-3,4-dihydroisoquinolin-1(2H)-one

Product 1

HCID 178456409HCID 178456409, compound

Reagents, catalysts & solvents 5

HCID 962WaterReagentHCID 62657Potassium Phosphate, TribasicReagentHCID 178454862HCID 178454862, compoundCatalystHCID 1140TolueneSolventHCID 117669-PhenylanthraceneInternal standard

Conditions

Temperature
110 °C

Sources & evidence

ORD record
ord-fca341c67f194685a930f26843c415a8
Source dataset
39k HTE dataset from Pfizer
Original link
View source

Reaction notes

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