Potassium Cation → 6-morpholino-3,4-dihydronaphthalen-1(2H)-one

HRID 201797Notes

Reaction equation

HRID 201797 reaction equation
[C:34]([P:35]([C:36]([CH3:37])([CH3:38])[CH3:39])[c:40]1[cH:41][cH:42][cH:43][cH:44][c:45]1-[c:46]1[cH:47][cH:48][cH:49][cH:50][cH:51]1)([CH3:52])([CH3:53])[CH3:54].[CH2:20]1[CH2:21][O:22][CH2:23][CH2:24][NH:25]1.[CH3:117][CH2:118][O:119][C:120](=[O:121])[CH3:122].[CH3:55][O:56][CH2:57][CH2:58][O:59][CH3:60].[CH:63](=[CH:64][C:65]([CH:66]=[CH:67][c:68]1[cH:69][cH:70][cH:71][cH:72][cH:73]1)=[O:74])[c:75]1[cH:76][cH:77][cH:78][cH:79][cH:80]1.[CH:81](=[CH:82][C:83]([CH:84]=[CH:85][c:86]1[cH:87][cH:88][cH:89][cH:90][cH:91]1)=[O:92])[c:93]1[cH:94][cH:95][cH:96][cH:97][cH:98]1.[CH:99](=[CH:100][C:101]([CH:102]=[CH:103][c:104]1[cH:105][cH:106][cH:107][cH:108][cH:109]1)=[O:110])[c:111]1[cH:112][cH:113][cH:114][cH:115][cH:116]1.[F:1][C:2]([F:3])([F:4])[S:5]([O:6][c:7]1[cH:8][c:9]2[c:14]([cH:15][cH:16]1)[C:13](=[O:17])[CH2:12][CH2:11][CH2:10]2)(=[O:18])=[O:19].[K+:31].[K+:32].[K+:33].[OH2:123].[P:26]([O-:27])([O-:28])([O-:29])=[O:30].[Pd:61].[Pd:62]>>[c:7]1([N:25]2[CH2:20][CH2:21][O:22][CH2:23][CH2:24]2)[cH:8][c:9]2[c:14]([cH:15][cH:16]1)[C:13](=[O:17])[CH2:12][CH2:11][CH2:10]2

Participants

11

Reactant 10

HCID 813Potassium Cation3×HCID 962WaterHCID 1061PhosphateHCID 80711,2-DimethoxyethaneHCID 8083MorpholineHCID 8857Ethyl AcetateHCID 23938Palladium2×HCID 95417Dibenzylidene acetone3×HCID 27342152-(Di-tert-butylphosphino)biphenylHCID 110983845-Oxo-5,6,7,8-tetrahydronaphthalen-2-yl trifluoromethanesulfonate

Product 1

HCID 131795016-morpholino-3,4-dihydronaphthalen-1(2H)-one

Sources & evidence

ORD record
ord-160787a290d8422e9531b3aebe09b16d
Source dataset
Training data from https://doi.org/10.1039/C8SC04228D (6/10)

Reaction notes

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