1-methyl-1H-pyrazol-4-amine → HCID 178480799, compound

HRID 2018041Notes

Reaction equation

HRID 2018041 reaction equation
[CH3:1][n:2]1[n:7][cH:6][c:4]([NH2:5])[cH:3]1.[CH3:8][N:9]([C:30]([O:32][C:33]([CH3:36])([CH3:35])[CH3:34])=[O:31])[C@H:10]1[CH2:13][C@H:12]([O:14][c:15]2[c:29]([c:19]3[n:18][c:17](Cl)[n:16]2)[c:22]([c:23]4[n:28][cH:27][cH:26][cH:25][cH:24]4)[cH:21][nH:20]3)[CH2:11]1>>[CH3:8][N:9]([C:30]([O:32][C:33]([CH3:36])([CH3:35])[CH3:34])=[O:31])[C@H:10]1[CH2:13][C@H:12]([O:14][c:15]2[c:29]([c:19]3[n:18][c:17]([NH:5][c:4]4[cH:3][n:2]([CH3:1])[n:7][cH:6]4)[n:16]2)[c:22]([c:23]5[n:28][cH:27][cH:26][cH:25][cH:24]5)[cH:21][nH:20]3)[CH2:11]1

Participants

7

Reactant 2

HCID 47709901-methyl-1H-pyrazol-4-amineHCID 178486066HCID 178486066, compound

Product 1

HCID 178480799HCID 178480799, compound

Reagents, catalysts & solvents 4

HCID 10796Cesium carbonateReagentHCID 178492614HCID 178492614, compoundCatalystHCID 64052-Methyl-2-butanolSolventHCID 117669-PhenylanthraceneInternal standard

Conditions

Temperature
110 °C

Sources & evidence

ORD record
ord-a5e7c037653945269a0ab018e1f531e8
Source dataset
39k HTE dataset from Pfizer
Original link
View source

Reaction notes

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