Hydrochloric Acid → Hydrochloric Acid

HRID 201863Notes

Reaction equation

HRID 201863 reaction equation
[C:1](#[N:2])[c:3]1[n:4][cH:5][cH:6][c:7]2[c:8]1[o:9][c:10](-[c:32]1[cH:33][cH:34][cH:35][cH:36][cH:37]1)[c:11](-[c:14]1[cH:15][cH:16][c:17]([C:20]3([NH:24][C:25](=[O:26])[O:27][C:28]([CH3:29])([CH3:30])[CH3:31])[CH2:21][CH2:22][CH2:23]3)[cH:18][cH:19]1)[c:12]2=[O:13].[CH2:42]1[O:43][CH2:44][CH2:45][O:46][CH2:47]1.[Cl:39][CH2:40][Cl:41].[ClH:38]>>[C:1](#[N:2])[c:3]1[n:4][cH:5][cH:6][c:7]2[c:8]1[o:9][c:10](-[c:32]1[cH:33][cH:34][cH:35][cH:36][cH:37]1)[c:11](-[c:14]1[cH:15][cH:16][c:17]([C:20]3([NH2:24])[CH2:21][CH2:22][CH2:23]3)[cH:18][cH:19]1)[c:12]2=[O:13].[ClH:38]

Participants

6

Reactant 4

HCID 313Hydrochloric AcidHCID 6344DichloromethaneHCID 312751,4-DioxaneHCID 68227519tert-butyl 1-(4-(8-cyano-4-oxo-2-phenyl-4H-pyrano[2,3-c]pyridin-3-yl)phenyl)cyclobutylcarbamate

Product 2

HCID 313Hydrochloric AcidHCID 670678713-[4-(1-Aminocyclobutyl)phenyl]-4-oxo-2-phenylpyrano[2,3-c]pyridine-8-carbonitrile

Sources & evidence

ORD record
ord-6cba59f4ffe144cea0effc7a07191c11
Source dataset
Training data from https://doi.org/10.1039/C8SC04228D (6/10)

Reaction notes

Loading…