2-Bromo-5-methoxypyridine → HCID 178490386, compound

HRID 2018657Notes

Reaction equation

HRID 2018657 reaction equation
[CH3:1][O:2][c:3]1[cH:8][n:7][c:6](Br)[cH:5][cH:4]1.[K+].[CH3:9][C:10]([O:13][C:14]([NH:16][CH2:17][CH2:18][B-](F)(F)F)=[O:15])([CH3:12])[CH3:11]>>[CH3:1][O:2][c:3]1[cH:8][n:7][c:6]([CH2:18][CH2:17][NH:16][C:14]([O:13][C:10]([CH3:12])([CH3:11])[CH3:9])=[O:15])[cH:5][cH:4]1

Participants

9

Reactant 2

HCID 111481512-Bromo-5-methoxypyridineHCID 42614635potassium tert-butyl N-(2-(trifluoroboranuidyl)ethyl)carbamate

Product 1

HCID 178490386HCID 178490386, compound

Reagents, catalysts & solvents 6

HCID 962WaterReagentHCID 10796Cesium carbonateReagentHCID 178420029HCID 178420029, compoundCatalystHCID 962WaterSolventHCID 1140TolueneSolventHCID 117669-PhenylanthraceneInternal standard

Conditions

Temperature
100 °C

Sources & evidence

ORD record
ord-5163cf7a60b74fa9aa57212de5d1a7dd
Source dataset
39k HTE dataset from Pfizer
Original link
View source

Reaction notes

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