HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 2018802Generated: October 29, 2026
Tert-butyl 4-(hydroxymethyl)piperidine-1-carboxylate → Tert-butyl 4-{[(4-aminopyrimidin-5-yl)oxy]methyl}piperidine-1-carboxylate
https://huagongshe.com/reaction/2018802
Participants
| Role | Name | HCID | Charge |
|---|
| Reactant | Tert-butyl 4-(hydroxymethyl)piperidine-1-carboxylate | HCID 2764081 | — |
| Reactant | 4-Amino-5-bromopyrimidine | HCID 10261576 | — |
| Reagent | Potassium t-amylate | HCID 23683543 | — |
| Catalyst | Pyrrole-2-Carboxylic Acid | HCID 12473 | — |
| Catalyst | Copper(1+) iodide; Copper(I) iodide; Cuprous iodide; Cuprous iodide (CuI) | HCID 24350 | — |
| Solvent | 1,4-Dioxane | HCID 31275 | — |
| Product | Tert-butyl 4-{[(4-aminopyrimidin-5-yl)oxy]methyl}piperidine-1-carboxylate | HCID 121409088 | — |
| Internal standard | 9-Phenylanthracene | HCID 11766 | — |
Provenance & Evidence
| DOI | 10.1038/s41557 |
|---|
| Source dataset | 39k HTE dataset from Pfizer |
|---|
| ORD ID | ord-af069de279a04e6fa661f066fb544fee |
|---|
| Source note | 39k HTE dataset from Pfizer |
|---|
