HCID 178453502, compound → HCID 178491794, compound

HRID 2018844Notes

Reaction equation

HRID 2018844 reaction equation

[CH3:1][C:2]([O:5][C:6]([NH:8][CH2:9][CH2:10][CH2:11][N:12]1[C:18](=[S:19])[NH:17][C:15](=[O:16])[CH:14]=[C:13]1I)=[O:7])([CH3:4])[CH3:3]>>COc1c([C:13]([N:12]([CH2:11][CH2:10][CH2:9][NH:8][C:6]([O:5][C:2]([CH3:4])([CH3:3])[CH3:1])=[O:7])[C:18](=[S:19])[NH:17][C:15]2=[O:16])=[CH:14]2)cc(F)cc1

Participants

7

Reactant 1

HCID 178453502HCID 178453502, compound

Product 1

HCID 178491794HCID 178491794, compound

Reagents, catalysts & solvents 5

HCID 962WaterReagent

HCID 25953Cesium fluorideReagent

HCID 75537289[1,1-bis(diphenylphosphino)ferrocene]dichloropalladium(II) dichlormethaneCatalyst

HCID 887MethanolSolvent

HCID 117669-PhenylanthraceneInternal standard

Conditions

Temperature: 80 °C

Sources & evidence

ORD record: ord-534c08433c6b4368b65884f78e75a85e
Source dataset: 39k HTE dataset from Pfizer
DOI: 10.1038/s41557
Original link: View source

Reaction notes

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