2,4-dichloro-5-iodo-7-tosyl-7H-pyrrolo[2,3-d]pyrimidine → HCID 178494802, compound

HRID 2018907Notes

Reaction equation

HRID 2018907 reaction equation
[CH3:1][c:2]1[cH:7][cH:6][c:5]([S:8]([n:11]2[c:21]([c:14]3[c:13](I)[cH:12]2)[n:20][c:18]([Cl:19])[n:17][c:15]3[Cl:16])(=[O:10])=[O:9])[cH:4][cH:3]1.[K+].[CH3:22][O:23][CH2:24][CH2:25][B-](F)(F)F>>[CH3:22][O:23][CH2:24][CH2:25][c:13]1[c:14]([c:21]2[n:11]([S:8]([c:5]3[cH:6][cH:7][c:2]([CH3:1])[cH:3][cH:4]3)(=[O:10])=[O:9])[cH:12]1)[c:15]([Cl:16])[n:17][c:18]([Cl:19])[n:20]2

Participants

8

Reactant 2

HCID 579902932,4-dichloro-5-iodo-7-tosyl-7H-pyrrolo[2,3-d]pyrimidineHCID 63701996PotassiuM (2-Methoxyethyl)trifluoroborate

Product 1

HCID 178494802HCID 178494802, compound

Reagents, catalysts & solvents 5

HCID 962WaterReagentHCID 10796Cesium carbonateReagentHCID 86278421[1,1'-bis(di-tert-butylphosphino) ferrocene]dichloropalladium(II)CatalystHCID 1140TolueneSolventHCID 117669-PhenylanthraceneInternal standard

Sources & evidence

ORD record
ord-118928a8934e48008af97288c66aca39
Source dataset
39k HTE dataset from Pfizer
Original link
View source

Reaction notes

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