1-Methyl-4-iodo-1H-pyrazole → HCID 178473412, compound

HRID 2019141Notes

Reaction equation

HRID 2019141 reaction equation
[CH3:1][CH2:2][O:3][C:4]([n:6]1[c:23]([c:10]2[c:8]([NH2:9])[n:7]1)[C:20]([CH3:22])([CH3:21])[N:12]([C:13]([O:15][C:16]([CH3:19])([CH3:18])[CH3:17])=[O:14])[CH2:11]2)=[O:5].[CH3:24][n:25]1[n:29][cH:28][c:27](I)[cH:26]1>>[CH3:1][CH2:2][O:3][C:4]([n:6]1[c:23]([c:10]2[c:8]([NH:9][c:27]3[cH:26][n:25]([CH3:24])[n:29][cH:28]3)[n:7]1)[C:20]([CH3:22])([CH3:21])[N:12]([C:13]([O:15][C:16]([CH3:19])([CH3:18])[CH3:17])=[O:14])[CH2:11]2)=[O:5]

Participants

6

Reactant 2

HCID 27347731-Methyl-4-iodo-1H-pyrazoleHCID 573530855-tert-Butyl 1-ethyl 3-amino-6,6-dimethyl-4,6-dihydropyrrolo[3,4-c]pyrazole-1,5-dicarboxylate

Product 1

HCID 178473412HCID 178473412, compound

Reagents, catalysts & solvents 3

HCID 10796Cesium carbonateReagentHCID 1140TolueneSolventHCID 117669-PhenylanthraceneInternal standard

Conditions

Temperature
100 °C

Sources & evidence

ORD record
ord-e0d87b61f486497193ea0565498de70c
Source dataset
39k HTE dataset from Pfizer
Original link
View source

Reaction notes

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