HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 2019362Generated: October 30, 2026
1-Chloro-4-iodobenzene → 6-(4-chlorophenyl)-1-methyl-4H-benzo[b][1,2,4]triazolo[4,3-d][1,4]diazepin-5(6H)-one
https://huagongshe.com/reaction/2019362
Participants
| Role | Name | HCID | Charge |
|---|
| Reactant | 1-Chloro-4-iodobenzene | HCID 12510 | — |
| Reactant | 1-Methyl-4,6-dihydro-[1,2,4]triazolo[4,3-a][1,5]benzodiazepin-5-one | HCID 101609891 | — |
| Reagent | Lithium Hexamethyldisilazide | HCID 2733832 | — |
| Catalyst | palladium(II) acetate | HCID 167845 | — |
| Solvent | Tetrahydrofuran | HCID 8028 | — |
| Product | 6-(4-chlorophenyl)-1-methyl-4H-benzo[b][1,2,4]triazolo[4,3-d][1,4]diazepin-5(6H)-one | HCID 70979528 | — |
| Internal standard | 9-Phenylanthracene | HCID 11766 | — |
Provenance & Evidence
| DOI | 10.1038/s41557 |
|---|
| Source dataset | 39k HTE dataset from Pfizer |
|---|
| ORD ID | ord-c45d97ff5f0c46179a20cf75f0ff3e2c |
|---|
| Source note | 39k HTE dataset from Pfizer |
|---|
