1-Chloro-4-iodobenzene → 6-(4-chlorophenyl)-1-methyl-4H-benzo[b][1,2,4]triazolo[4,3-d][1,4]diazepin-5(6H)-one
Reaction equation
[CH3:1][c:2]1[n:16]([c:5]2[n:4][n:3]1)[c:15]([c:10]3[NH:9][C:7](=[O:8])[CH2:6]2)[cH:14][cH:13][cH:12][cH:11]3.[Cl:17][c:18]1[cH:23][cH:22][c:21](I)[cH:20][cH:19]1>>[CH3:1][c:2]1[n:16]([c:5]2[n:4][n:3]1)[c:15]([c:10]3[N:9]([c:21]4[cH:22][cH:23][c:18]([Cl:17])[cH:19][cH:20]4)[C:7](=[O:8])[CH2:6]2)[cH:14][cH:13][cH:12][cH:11]3Participants
7
Reactant 2
Product 1
Reagents, catalysts & solvents 4
Conditions
- Temperature
- 110 °C
Sources & evidence
- ORD record
- ord-c45d97ff5f0c46179a20cf75f0ff3e2c
- Source dataset
- 39k HTE dataset from Pfizer
- Original link
- View source
Reaction notes
Loading…